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Olfactory dysfunction

near OR5M8 · rs627933

What the study found

Who was studied 22,730 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 8 × 10−9.

Where it sits Chromosome 11, band 11q12.1 — in a non-coding transcript of OR5M7P.

What each result means

A/A No copy of the version the research linked to Olfactory dysfunction. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Olfactory dysfunction. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Olfactory dysfunction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs627933

What is rs627933?

rs627933 is a single position in the genome, in or near the near OR5M8 gene. Published research associates it with olfactory dysfunction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs627933 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs627933 come from?

GWAS Catalog, BMC genomic data 2025, PMID:40963118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Olfactory dysfunction (rs627933). MyGeneLog™. https://www.mygenelog.com/variants/rs627933

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