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Blood protein levels in cardiovascular risk

CCR5 · rs62625034

What the study found

Who was studied 3,394 European ancestry individuals; replicated in 2,639 individuals.

The effect Each copy of the G allele shifted the measure 0.55 lower; p = 8 × 10−83.

How common The G allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — a missense change in CCR5.

What each result means

G/G Two copies of the version the research linked to Blood protein levels in cardiovascular risk. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Blood protein levels in cardiovascular risk. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blood protein levels in cardiovascular risk. This is the starting point the study compared everyone against.
Source

Questions about rs62625034

What is rs62625034?

rs62625034 is a single position in the genome, in or near the CCR5 gene. Published research associates it with blood protein levels in cardiovascular risk. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62625034 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62625034 come from?

GWAS Catalog, PLoS genetics 2017, PMID:28369058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Blood protein levels in cardiovascular risk (rs62625034). MyGeneLog™. https://www.mygenelog.com/variants/rs62625034

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