Standard

Trypsin-2 levels (PRSS2.5034.79.1)

near EPHB6 · rs62473589

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.35 lower (95% confidence interval -0.27--0.43); p = 4 × 10−15.

How common The G allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 7, band 7q34 — between genes, 10.2 kb from EPHB6.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Trypsin-2 levels (PRSS2.5034.79.1) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Trypsin-2 levels (PRSS2.5034.79.1).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Trypsin-2 levels (PRSS2.5034.79.1) compared to the general population.
Source

Questions about rs62473589

What is rs62473589?

rs62473589 is a single position in the genome, in or near the near EPHB6 gene. Published research associates it with trypsin-2 levels (prss2.5034.79.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62473589 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62473589 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Trypsin-2 levels (PRSS2.5034.79.1) (rs62473589). MyGeneLog™. https://www.mygenelog.com/variants/rs62473589

← See all variants