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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,522 Finnish ancestry cases, 451,091 Finnish ancestry controls; replicated in 173 cases, 419,453 controls.
The effect
Each copy of the T allele shifted the measure 0.218 higher (95% confidence interval 0.15-0.28); p = 2 × 10−10.
How common The T allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 6, band 6q25.1 — in an intron of PLEKHG1.
What each result means
C/CNo copy of the version the research linked to Normal pressure hydrocephalus. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Normal pressure hydrocephalus. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Normal pressure hydrocephalus. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs62434144 is a single position in the genome, in or near the PLEKHG1 gene. Published research associates it with normal pressure hydrocephalus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs62434144 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs62434144 come from?
GWAS Catalog, Neurology 2024, PMID:39141892. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Normal pressure hydrocephalus (rs62434144). MyGeneLog™. https://www.mygenelog.com/variants/rs62434144