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Uterine fibroids

LNX1 · rs62323680

Where this position leads

Condition: Uterine Fibroids

rs62323680 Condition: Uterine Fibroids Uterine Fibroids Condition rs62323680 rs62323680 LNX1

What the study found

Who was studied 14,905 East Asian ancestry female cases, 69,609 East Asian ancestry female controls, 14,905 Central Asian ancestry female cases, 69,609 Central Asian ancestry female controls, 14,905 South Asian ancestry female cases, 69,609 South Asian ancestry female controls.

The effect Each copy of the A allele shifted the measure 0.163 higher (95% confidence interval 0.12-0.21); p = 9 × 10−13.

Where it sits Chromosome 4, band 4q12 — in an intron of LNX1.

What each result means

A/A Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
G/G No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
Source

Questions about rs62323680

What is rs62323680?

rs62323680 is a single position in the genome, in or near the LNX1 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62323680 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs62323680 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62323680 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine fibroids (rs62323680). MyGeneLog™. https://www.mygenelog.com/variants/rs62323680

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