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Who was studied 13,047 European ancestry cases, 262,499 European ancestry controls; replicated in 4,450 European ancestry cases, 87,398 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−10.
How common The T allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 3, band 3p14.3 — in an intron of ERC2.
What each result means
G/GNo copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Hernia : the journal of hernias and abdominal wall surgery · 2022 · PMID 34382107
Questions about rs62251475
What is rs62251475?
rs62251475 is a single position in the genome, in or near the ERC2 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs62251475 linked to?
On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.
Does having rs62251475 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs62251475 come from?
GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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