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Nasal polyps

FOXP1 · rs62247034

Where this position leads

Condition: Chronic Rhinosinusitis with Nasal Polyps

rs62247034 Condition: Chronic Rhinosinusitis with Nasal Polyps Chronic Rhinosinusitis with Nasal Polyps Condition rs62247034 rs62247034 FOXP1

What the study found

Who was studied 5,093 European ancestry cases, 444,966 European ancestry controls, 160 East Asian ancestry cases, 151,846 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.165 lower (95% confidence interval 0.12-0.21); p = 8 × 10−14.

Where it sits Chromosome 3, band 3p13 — in an intron of FOXP1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Nasal polyps compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Nasal polyps.
C/C Published research associates this genotype with typical/baseline likelihood of Nasal polyps — no copies of the reported risk allele.
Source

Questions about rs62247034

What is rs62247034?

rs62247034 is a single position in the genome, in or near the FOXP1 gene. Published research associates it with nasal polyps. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62247034 linked to?

On MyGeneLog this position is linked to Chronic Rhinosinusitis with Nasal Polyps. The research behind each link, and its sources, are set out on that condition page.

Does having rs62247034 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62247034 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Nasal polyps (rs62247034). MyGeneLog™. https://www.mygenelog.com/variants/rs62247034

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