SLC6A6 · rs62233562
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 94 cases from twins, 1,036 controls from twins.
The effect Each copy of the G allele carried 3.11 times the odds of Revision surgery after total joint arthroplasty (95% confidence interval 2.19-4.4); p = 2 × 10−10.
How common The G allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 3, band 3p25.1 — in an intron of SLC6A6.
rs62233562 is a single position in the genome, in or near the SLC6A6 gene. Published research associates it with revision surgery after total joint arthroplasty. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, The Journal of bone and joint surgery. American volume 2022, PMID:34982741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Revision surgery after total joint arthroplasty (rs62233562). MyGeneLog™. https://www.mygenelog.com/variants/rs62233562