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Hip index

SLC24A3 · rs62200371

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−13, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 219,872 British ancestry women.

The effect Each copy of the A allele shifted the measure 0.0227 higher (95% confidence interval 0.017-0.029); p = 2 × 10−13.

Where it sits Chromosome 20, band 20p11.23 — in an intron of SLC24A3.

What each result means

A/A Two copies of the version the research linked to Hip index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hip index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hip index. This is the starting point the study compared everyone against.
Source

Questions about rs62200371

What is rs62200371?

rs62200371 is a single position in the genome, in or near the SLC24A3 gene. Published research associates it with hip index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62200371 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62200371 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hip index (rs62200371). MyGeneLog™. https://www.mygenelog.com/variants/rs62200371

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