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Depressive symptom (sleep problems) (binary trait)

CBWD2 · rs62158169

What the study found

Who was studied 72,302 European ancestry cases, 76,450 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.015 higher (95% confidence interval 0.011-0.019); p = 1 × 10−10.

How common The C allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 2, band 2q14.1 — in an intron of LINC02966.

What each result means

C/C Two copies of the version the research linked to Depressive symptom (sleep problems) (binary trait). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Depressive symptom (sleep problems) (binary trait). That is a smaller link than two copies.
T/T No copy of the version the research linked to Depressive symptom (sleep problems) (binary trait). This is the starting point the study compared everyone against.
Source

Questions about rs62158169

What is rs62158169?

rs62158169 is a single position in the genome, in or near the CBWD2 gene. Published research associates it with depressive symptom (sleep problems) (binary trait). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62158169 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62158169 come from?

GWAS Catalog, Psychological medicine 2020, PMID:31530331. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Depressive symptom (sleep problems) (binary trait) (rs62158169). MyGeneLog™. https://www.mygenelog.com/variants/rs62158169

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