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Psoriasis

FLJ16341 · rs62149416

Where this position leads

Condition: Psoriasis

rs62149416 Condition: Psoriasis Psoriasis Condition rs62149416 rs62149416 FLJ16341

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Psoriasis — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Psoriasis.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Psoriasis compared to the general population.
Source
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH
and 53 more — show all
McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC
Collaborative Association Study of Psoriasis (CASP) · Genetic Analysis of Psoriasis Consortium · Psoriasis Association Genetics Extension · Wellcome Trust Case Control Consortium 2
Nature genetics · 2012 · PMID 23143594 · open access

Questions about rs62149416

What is rs62149416?

rs62149416 is a single position in the genome, in or near the FLJ16341 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62149416 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs62149416 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62149416 come from?

GWAS Catalog, Nat Genet 2012, PMID:23143594. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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