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Energy expenditure

VSNL1 · rs62131523

What the study found

Who was studied 5,461 European ancestry lean females, 2,726 European ancestry lean males, 6,563 European ancestry overweight or obese females, 4,020 European ancestry overweight or obese males..

The effect Each copy of the G allele shifted the measure 124 kcals higher (95% confidence interval 80-169); p = 3 × 10−8.

How common The G allele had a frequency of about 96% in the people studied.

Where it sits Chromosome 2, band 2p24.2 — in an intron of VSNL1.

What each result means

A/A No copy of the version the research linked to Energy expenditure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Energy expenditure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Energy expenditure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62131523

What is rs62131523?

rs62131523 is a single position in the genome, in or near the VSNL1 gene. Published research associates it with energy expenditure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62131523 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62131523 come from?

GWAS Catalog, PLoS One 2018, PMID:30071075. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Energy expenditure (rs62131523). MyGeneLog™. https://www.mygenelog.com/variants/rs62131523

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