BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation
ADGRE1 · rs62123082
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Who was studied 496 European ancestry individuals; replicated in 527 individuals.
The effect
Each copy of the G allele shifted the measure 7 higher (95% confidence interval 4.84-9.16); p = 3 × 10−10.
Where it sits Chromosome 19, band 19p13.2 — in an intron of ADGRE1.
What each result means
A/ANo copy of the version the research linked to BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs62123082 is a single position in the genome, in or near the ADGRE1 gene. Published research associates it with bmi in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs62123082 linked to?
On MyGeneLog this position is linked to Acute Lymphoblastic Leukemia. The research behind each link, and its sources, are set out on that condition page.
Does having rs62123082 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs62123082 come from?
GWAS Catalog, Cancer 2021, PMID:33048379. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation (rs62123082). MyGeneLog™. https://www.mygenelog.com/variants/rs62123082