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Triglyceride to phosphoglyceride ratio

SH3YL1 · rs62114505

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the G allele shifted the measure 0.01 ratio higher (95% confidence interval 0.01-0.01); p = 2 × 10−10.

Where it sits Chromosome 2, band 2p25.3 — in an intron of SH3YL1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Triglyceride to phosphoglyceride ratio — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglyceride to phosphoglyceride ratio.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglyceride to phosphoglyceride ratio compared to the general population.
Source

Questions about rs62114505

What is rs62114505?

rs62114505 is a single position in the genome, in or near the SH3YL1 gene. Published research associates it with triglyceride to phosphoglyceride ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62114505 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62114505 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglyceride to phosphoglyceride ratio (rs62114505). MyGeneLog™. https://www.mygenelog.com/variants/rs62114505

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