Standard

Triglyceride levels in chylomicrons and extremely large VLDL

PEPD · rs62102718

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs62102718 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs62102718 rs62102718 PEPD

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.02 mmol/L lower (95% confidence interval 0.02-0.02); p = 1 × 10−16.

Where it sits Chromosome 19, band 19q13.11 — in an intron of PEPD.

What each result means

A/A No copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62102718

What is rs62102718?

rs62102718 is a single position in the genome, in or near the PEPD gene. Published research associates it with triglyceride levels in chylomicrons and extremely large vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62102718 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs62102718 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62102718 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglyceride levels in chylomicrons and extremely large VLDL (rs62102718). MyGeneLog™. https://www.mygenelog.com/variants/rs62102718

← See all variants