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Smoking initiation

DCC · rs62098013

What the study found

Who was studied 2,669,029 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.00889 higher (95% confidence interval 0.0071-0.0107); p = 5 × 10−23.

How common The A allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 18, band 18q21.2 — in an intron of DCC.

What each result means

A/A Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
G/G No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
Source

Questions about rs62098013

What is rs62098013?

rs62098013 is a single position in the genome, in or near the DCC gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62098013 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62098013 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Smoking initiation (rs62098013). MyGeneLog™. https://www.mygenelog.com/variants/rs62098013

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