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Monocyte count

VMP1 · rs62081824

Where this position leads

What the study found

Who was studied 38,000 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.127 lower (95% confidence interval 0.1-0.154); p = 2 × 10⁻²⁰.

Where it sits Chromosome 17, band 17q23.1 — in an intron of VMP1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Monocyte count — no copies of the reported risk allele.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte count.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte count compared to the general population.

Source

Genetic architecture of routinely acquired blood tests in a British South Asian cohort

Jacobs BM, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Walter K, Langenberg C, Dobson R, Finer S, Morton C

and 5 more — show all

Siddiqui MK, Martin HC, Pietzner M, Mathur R, van Heel DA

Genes & Health Research Team

Nature communications · 2024 · PMID 39414775 · open access

Questions about rs62081824

What is rs62081824?

rs62081824 is a single position in the genome, in or near the VMP1 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62081824 linked to?

On MyGeneLog this position is linked to Monocyte Count. The research behind each link, and its sources, are set out on that condition page.

Does having rs62081824 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62081824 come from?

GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Monocyte count (rs62081824). MyGeneLog™. https://www.mygenelog.com/variants/rs62081824

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