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Total testosterone levels

SHBG · rs62059839

What the study found

Who was studied 148,248 British ancestry men.

The effect Each copy of the T allele shifted the measure 0.72 nmol/L higher (95% confidence interval 0.68-0.76); p = 3 × 10−289.

How common The T allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of SHBG.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Total testosterone levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total testosterone levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total testosterone levels compared to the general population.
Source

Questions about rs62059839

What is rs62059839?

rs62059839 is a single position in the genome, in or near the SHBG gene. Published research associates it with total testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62059839 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62059839 come from?

GWAS Catalog, Science advances 2021, PMID:34321204. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total testosterone levels (rs62059839). MyGeneLog™. https://www.mygenelog.com/variants/rs62059839

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