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Cortical surface area

LINC02210-CRHR1 · rs62057070

What the study found

Who was studied 33,992 European ancestry individuals; replicated in 14,727 European ancestry individuals, 2,943 individuals.

The effect Each copy of the A allele shifted the measure 17.6 higher (95% confidence interval 12.86-22.42); p = 5 × 10−13.

How common The A allele had a frequency of about 79% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — in an intron of LINC02210-CRHR1.

What each result means

A/A Two copies of the version the research linked to Cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs62057070

What is rs62057070?

rs62057070 is a single position in the genome, in or near the LINC02210-CRHR1 gene. Published research associates it with cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62057070 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62057070 come from?

GWAS Catalog, Science (New York, N.Y.) 2020, PMID:32193296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical surface area (rs62057070). MyGeneLog™. https://www.mygenelog.com/variants/rs62057070

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