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Depressed affect

LINC02210-CRHR1 · rs62057061

What the study found

Who was studied 357,957 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0269 higher (95% confidence interval 0.021-0.032); p = 2 × 10−22.

Where it sits Chromosome 17, band 17q21.31 — in an intron of LINC02210-CRHR1.

What each result means

C/C No copy of the version the research linked to Depressed affect. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Depressed affect. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Depressed affect. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62057061

What is rs62057061?

rs62057061 is a single position in the genome, in or near the LINC02210-CRHR1 gene. Published research associates it with depressed affect. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62057061 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62057061 come from?

GWAS Catalog, Nature genetics 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Depressed affect (rs62057061). MyGeneLog™. https://www.mygenelog.com/variants/rs62057061

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