Standard

Waist circumference

ATXN2L · rs62036624

Where this position leads

Condition: Waist Circumference

rs62036624 Condition: Waist Circumference Waist Circumference Condition rs62036624 rs62036624 ATXN2L

What the study found

Who was studied 1,254 whole genome sequenced European ancestry individuals, 3,072 whole genome sequenced individuals, 41,450 European ancestry individuals, 397 Carlantino (founder/genetic isolate) individuals, 791 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,060 Mylopotamos (founder/genetic isolate) individuals, 887 Pomak (founder/genetic isolate) individuals, 1,754 Val Borbera (founder/genetic isolate) individuals; replicated in 206,737 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0384 higher (95% confidence interval 0.025-0.052); p = 4 × 10−8.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 16, band 16p11.2 — in an intron of ATXN2L.

What each result means

G/G No copy of the version the research linked to Waist circumference. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Waist circumference. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Waist circumference. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs62036624

What is rs62036624?

rs62036624 is a single position in the genome, in or near the ATXN2L gene. Published research associates it with waist circumference. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs62036624 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs62036624 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62036624 come from?

GWAS Catalog, American journal of human genetics 2017, PMID:28552196. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist circumference (rs62036624). MyGeneLog™. https://www.mygenelog.com/variants/rs62036624

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