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Vertex-wise cortical surface area

WWOX · rs62033986

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 6.37 z score higher; p = 2 × 10−10.

How common The C allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 16, band 16q23.1 — in an intron of WWOX.

What each result means

C/C Two copies of the version the research linked to Vertex-wise cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Vertex-wise cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Vertex-wise cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs62033986

What is rs62033986?

rs62033986 is a single position in the genome, in or near the WWOX gene. Published research associates it with vertex-wise cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62033986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62033986 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertex-wise cortical surface area (rs62033986). MyGeneLog™. https://www.mygenelog.com/variants/rs62033986

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