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Cerebellar grey matter morphology (MOSTest)

RORA · rs62002749

What the study found

Who was studied 27,302 European ancestry individuals; replicated in 11,264 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 9 × 10−10.

Where it sits Chromosome 15, band 15q22.2 — in an intron of RORA.

What each result means

A/A Two copies of the version the research linked to Cerebellar grey matter morphology (MOSTest). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cerebellar grey matter morphology (MOSTest). That is a smaller link than two copies.
G/G No copy of the version the research linked to Cerebellar grey matter morphology (MOSTest). This is the starting point the study compared everyone against.
Source

Questions about rs62002749

What is rs62002749?

rs62002749 is a single position in the genome, in or near the RORA gene. Published research associates it with cerebellar grey matter morphology (mostest). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62002749 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62002749 come from?

GWAS Catalog, Communications biology 2026, PMID:41703085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cerebellar grey matter morphology (MOSTest) (rs62002749). MyGeneLog™. https://www.mygenelog.com/variants/rs62002749

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