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Sleep duration

PRIMA1 · rs61980273

Where this position leads

Condition: Sleep and Circadian Rhythm

rs61980273 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs61980273 rs61980273 PRIMA1

What the study found

Who was studied 112,411 European ancestry male individuals.

The effect Each copy of the A allele shifted the measure 0.06 higher (95% confidence interval 0.038-0.082); p = 4 × 10−8.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 14, band 14q32.12 — in an intron of PRIMA1.

What each result means

A/A Two copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
Source

Questions about rs61980273

What is rs61980273?

rs61980273 is a single position in the genome, in or near the PRIMA1 gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61980273 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs61980273 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61980273 come from?

GWAS Catalog, Nat Genet 2017, PMID:28604731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (rs61980273). MyGeneLog™. https://www.mygenelog.com/variants/rs61980273

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