KLF12 · rs61957289
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,461 European ancestry lean females, 2,726 European ancestry lean males, 6,563 European ancestry overweight or obese females, 4,020 European ancestry overweight or obese males..
The effect Each copy of the C allele shifted the measure 53 kcals higher (95% confidence interval 35-72); p = 1 × 10−8.
How common The C allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 13, band 13q22.1 — in an intron of KLF12.
rs61957289 is a single position in the genome, in or near the KLF12 gene. Published research associates it with energy expenditure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS One 2018, PMID:30071075. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Energy expenditure (rs61957289). MyGeneLog™. https://www.mygenelog.com/variants/rs61957289