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Triglyceride to HDL cholesterol ratio

SCARB1 · rs61941660

What the study found

Who was studied 402,398 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0414 higher (95% confidence interval 0.033-0.05); p = 1 × 10−13.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of SCARB1.

What each result means

C/C Two copies of the version the research linked to Triglyceride to HDL cholesterol ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Triglyceride to HDL cholesterol ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglyceride to HDL cholesterol ratio. This is the starting point the study compared everyone against.
Source

Questions about rs61941660

What is rs61941660?

rs61941660 is a single position in the genome, in or near the SCARB1 gene. Published research associates it with triglyceride to hdl cholesterol ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61941660 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61941660 come from?

GWAS Catalog, Nature genetics 2024, PMID:38200128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride to HDL cholesterol ratio (rs61941660). MyGeneLog™. https://www.mygenelog.com/variants/rs61941660

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