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Cardiovascular delta age (difference between cardiac MRI-predicted and chronological age)

PLCE1 · rs61886308

What the study found

Who was studied 29,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.56 higher (95% confidence interval 0.4-0.72); p = 2 × 10−11.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 10, band 10q23.33 — in an intron of PLCE1.

What each result means

A/A Two copies of the version the research linked to Cardiovascular delta age (difference between cardiac MRI-predicted and chronological age). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cardiovascular delta age (difference between cardiac MRI-predicted and chronological age). That is a smaller link than two copies.
G/G No copy of the version the research linked to Cardiovascular delta age (difference between cardiac MRI-predicted and chronological age). This is the starting point the study compared everyone against.
Source

Questions about rs61886308

What is rs61886308?

rs61886308 is a single position in the genome, in or near the PLCE1 gene. Published research associates it with cardiovascular delta age (difference between cardiac mri-predicted and chronological age). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61886308 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61886308 come from?

GWAS Catalog, Nature communications 2023, PMID:37604819. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Cardiovascular delta age (difference between cardiac MRI-predicted and chronological age) (rs61886308). MyGeneLog™. https://www.mygenelog.com/variants/rs61886308

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