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Cholesteryl Esters to Total Lipids in Large HDL percentage

ARL14EP-DT · rs61886116

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs61886116 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs61886116 rs61886116 ARL14EP-DT

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.01 % lower (95% confidence interval 0.01-0.01); p = 2 × 10−13.

Where it sits Chromosome 11, band 11p14.1 — in an intron of ARL14EP-DT.

What each result means

G/G No copy of the version the research linked to Cholesteryl Esters to Total Lipids in Large HDL percentage. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Cholesteryl Esters to Total Lipids in Large HDL percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cholesteryl Esters to Total Lipids in Large HDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61886116

What is rs61886116?

rs61886116 is a single position in the genome, in or near the ARL14EP-DT gene. Published research associates it with cholesteryl esters to total lipids in large hdl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61886116 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs61886116 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61886116 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesteryl Esters to Total Lipids in Large HDL percentage (rs61886116). MyGeneLog™. https://www.mygenelog.com/variants/rs61886116

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