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Low density lipoprotein cholesterol levels

GATD1-DT · rs61876729

What the study found

Who was studied 431,167 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0205 higher (95% confidence interval 0.014-0.027); p = 6 × 10−10.

How common The A allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 11, band 11p15.5 — in an intron of GATD1-DT.

What each result means

A/A Two copies of the version the research linked to Low density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Low density lipoprotein cholesterol levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Low density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs61876729

What is rs61876729?

rs61876729 is a single position in the genome, in or near the GATD1-DT gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61876729 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61876729 come from?

GWAS Catalog, Diabetes 2020, PMID:32493714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Low density lipoprotein cholesterol levels (rs61876729). MyGeneLog™. https://www.mygenelog.com/variants/rs61876729

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