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Kidney sinus volume

SUFU · rs61871137

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−13, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 38,816 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.15 higher (95% confidence interval 0.11-0.19); p = 3 × 10−13.

How common The C allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 10, band 10q24.32 — in an intron of SUFU.

How common each version is

CT
Japanese ToMMo
C 100.0%
World gnomAD
C 98.3% · T 1.7%
World 1000 Genomes
C 98.8% · T 1.2%
World TOPMed
C 98.2% · T 1.8%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. No Korean figure for this position yet.

What each result means

C/C Two copies of the version the research linked to Kidney sinus volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Kidney sinus volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Kidney sinus volume. This is the starting point the study compared everyone against.
Source

Questions about rs61871137

What is rs61871137?

rs61871137 is a single position in the genome, in or near the SUFU gene. Published research associates it with kidney sinus volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61871137 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61871137 come from?

GWAS Catalog, Kidney international 2026, PMID:41077127. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Kidney sinus volume (rs61871137). MyGeneLog™. https://www.mygenelog.com/variants/rs61871137

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