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Triglycerides to Total Lipids in Large LDL percentage

SGMS1 · rs61856787

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs61856787 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs61856787 rs61856787 SGMS1

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.02 % lower (95% confidence interval 0.02-0.02); p = 2 × 10−11.

Where it sits Chromosome 10, band 10q11.23 — in an intron of SGMS1.

What each result means

C/C No copy of the version the research linked to Triglycerides to Total Lipids in Large LDL percentage. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglycerides to Total Lipids in Large LDL percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides to Total Lipids in Large LDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61856787

What is rs61856787?

rs61856787 is a single position in the genome, in or near the SGMS1 gene. Published research associates it with triglycerides to total lipids in large ldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61856787 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs61856787 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61856787 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides to Total Lipids in Large LDL percentage (rs61856787). MyGeneLog™. https://www.mygenelog.com/variants/rs61856787

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