Standard

Skin condition (ex. Eczema, Psoriasis)

near RPL32P23 · rs61839672

Where this position leads

Condition: Psoriasis

rs61839672 Condition: Psoriasis Psoriasis Condition rs61839672 rs61839672 near RPL32P23

What the study found

Who was studied 6,069 African American or Afro-Caribbean cases, 49,436 African American or Afro-Caribbean controls, 3,028 Hispanic or Latin American cases, 26,286 Hispanic or Latin American controls, 563 East Asian ancestry cases, 2,984 East Asian ancestry controls, 32,976 European ancestry cases, 282,692 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.122 lower (95% confidence interval 0.099-0.145); p = 1 × 10−19.

How common The G allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 10, band 10p15.1 — between genes, 1.5 kb from RPL32P23.

What each result means

A/A No copy of the version the research linked to Skin condition (ex. Eczema, Psoriasis). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Skin condition (ex. Eczema, Psoriasis). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Skin condition (ex. Eczema, Psoriasis). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61839672

What is rs61839672?

rs61839672 is a single position in the genome, in or near the near RPL32P23 gene. Published research associates it with skin condition (ex. eczema, psoriasis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61839672 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs61839672 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61839672 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Skin condition (ex. Eczema, Psoriasis) (rs61839672). MyGeneLog™. https://www.mygenelog.com/variants/rs61839672

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