Standard

Pulse pressure

PAPPA2 · rs61823001

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pulse pressure compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pulse pressure.

G/G Published research associates this genotype with typical/baseline likelihood of Pulse pressure — no copies of the reported risk allele.

Source

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

Hoffmann TJ, Ehret GB, Nandakumar P, Ranatunga D, Schaefer C, Kwok PY, Iribarren C, Chakravarti A, Risch N

Nature genetics · 2017 · PMID 27841878 · open access

Questions about rs61823001

What is rs61823001?

rs61823001 is a single position in the genome, in or near the PAPPA2 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61823001 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61823001 come from?

GWAS Catalog, Nat Genet 2016, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants