A/APublished research associates this genotype with typical/baseline likelihood of Cerebrospinal fluid levels of Alzheimer's disease-related proteins — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cerebrospinal fluid levels of Alzheimer's disease-related proteins.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cerebrospinal fluid levels of Alzheimer's disease-related proteins compared to the general population.
PLoS genetics · 2014 · PMID 25340798 · open access
Questions about rs61812598
What is rs61812598?
rs61812598 is a single position in the genome, in or near the IL6R gene. Published research associates it with cerebrospinal fluid levels of alzheimer's disease-related proteins. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs61812598 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs61812598 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs61812598 come from?
GWAS Catalog, PLoS Genet 2014, PMID:25340798. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.