Sensitive

Cerebrospinal fluid levels of Alzheimer's disease-related proteins

IL6R · rs61812598

Where this position leads

Condition: Alzheimer's Disease

rs61812598 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs61812598 rs61812598 IL6R

What the study found

Who was studied 574 individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 6 × 10−63.

Where it sits Chromosome 1, band 1q21.3 — in an intron of IL6R.

What each result means

A/A No copy of the version the research linked to Cerebrospinal fluid levels of Alzheimer's disease-related proteins. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Cerebrospinal fluid levels of Alzheimer's disease-related proteins. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Cerebrospinal fluid levels of Alzheimer's disease-related proteins. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61812598

What is rs61812598?

rs61812598 is a single position in the genome, in or near the IL6R gene. Published research associates it with cerebrospinal fluid levels of alzheimer's disease-related proteins. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61812598 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs61812598 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61812598 come from?

GWAS Catalog, PLoS Genet 2014, PMID:25340798. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cerebrospinal fluid levels of Alzheimer's disease-related proteins (rs61812598). MyGeneLog™. https://www.mygenelog.com/variants/rs61812598

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