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Body mass index

SLC2A2 · rs61791109

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

Drug: Metformin

rs61791109 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition Drug: Metformin Metformin Drug rs61791109 rs61791109 SLC2A2

What the study found

Who was studied 441,761 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0176 lower (95% confidence interval 0.013-0.022); p = 9 × 10−17.

Where it sits Chromosome 3, band 3q26.2 — in an intron of SLC2A2.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61791109

What is rs61791109?

rs61791109 is a single position in the genome, in or near the SLC2A2 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61791109 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does rs61791109 affect how medicines work?

SLC2A2 carries pharmacogenomic findings for Metformin. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs61791109 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61791109 come from?

GWAS Catalog, Diabetologia 2023, PMID:37280435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs61791109). MyGeneLog™. https://www.mygenelog.com/variants/rs61791109

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