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Male-pattern baldness

FOXD2 · rs61784834

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs61784834 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs61784834 rs61784834 FOXD2

What the study found

Who was studied 25,662 British ancestry cases, 17,928 British ancestry controls; replicated in 13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls.

The effect Each copy of the C allele shifted the measure 0.0975 higher (95% confidence interval 0.07-0.125); p = 7 × 10−12.

Where it sits Chromosome 1, band 1p33 — between genes, 11.3 kb from RPL21P24.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
T/T Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
Source

Questions about rs61784834

What is rs61784834?

rs61784834 is a single position in the genome, in or near the FOXD2 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61784834 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs61784834 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61784834 come from?

GWAS Catalog, Nat Commun 2017, PMID:29146897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs61784834). MyGeneLog™. https://www.mygenelog.com/variants/rs61784834

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