Standard

Mean corpuscular hemoglobin

PPIEL · rs61779359

Where this position leads

Condition: Blood Cell Counts

rs61779359 Condition: Blood Cell Counts Blood Cell Counts Condition rs61779359 rs61779359 PPIEL

What the study found

Who was studied 350,472 European ancestry individuals, 128,028 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0314 lower (95% confidence interval 0.027-0.036); p = 1 × 10−37.

Where it sits Chromosome 1, band 1p34.3 — in an intron of PPIEL.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
Source

Questions about rs61779359

What is rs61779359?

rs61779359 is a single position in the genome, in or near the PPIEL gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61779359 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs61779359 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61779359 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin (rs61779359). MyGeneLog™. https://www.mygenelog.com/variants/rs61779359

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