Standard

Medication use (antimigraine preparations)

PRDM16 · rs61759167

Where this position leads

Condition: Migraine

rs61759167 Condition: Migraine Migraine Condition rs61759167 rs61759167 PRDM16

What the study found

Who was studied 5,521 European ancestry cases, 114,323 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.151 higher (95% confidence interval 0.11-0.2); p = 8 × 10−11.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 1, band 1p36.32 — in an intron of PRDM16.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (antimigraine preparations) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (antimigraine preparations).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (antimigraine preparations) compared to the general population.
Source

Questions about rs61759167

What is rs61759167?

rs61759167 is a single position in the genome, in or near the PRDM16 gene. Published research associates it with medication use (antimigraine preparations). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61759167 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

Does having rs61759167 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61759167 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (antimigraine preparations) (rs61759167). MyGeneLog™. https://www.mygenelog.com/variants/rs61759167

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