PPP1R9A · rs61737465
Where this position leads
Condition: Insomnia
Strength of the evidence
Its strongest genetic-study result is p = 10−7, with 1 associations in the GWAS Catalog.
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 390,751 European ancestry female cases, 1,018,386 European ancestry female controls.
The effect Each copy of the A allele shifted the measure 0.012 higher (95% confidence interval 0.0081-0.0159); p = 4 × 10−8.
Where it sits Chromosome 7, band 7q21.3 — a missense change in PPP1R9A.
What ClinVar records
Classification
Benign for PPP1R9A-related disorder; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2019-06-11.
ClinVar record 3059917 NM_001166160.2(PPP1R9A):c.1102G>A (p.Asp368Asn)
Change history MyGeneLog™ keeps a copy of every weekly release from 2026-10-19 and compares them. This position's classification has not changed since.
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs61737465 is a single position in the genome, in or near the PPP1R9A gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Insomnia (rs61737465). MyGeneLog™. https://www.mygenelog.com/variants/rs61737465