0 16122227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 147,997 European ancestry cases, 575,269 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0109 higher (95% confidence interval 0.0072-0.0146); p = 8 × 10−9.
How common The T allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 20, band 20q13.33 — a missense change in COL9A3.
What ClinVar records
ClassificationBenign/Likely benign for Intervertebral disc disease, susceptibility to, Connective tissue disorder, Uterine corpus endometrial carcinoma, Colon adenocarcinoma, Uveal melanoma and 6 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 15 submitters), last evaluated 2026-05-09.
ClinVar record 17139NM_001853.4(COL9A3):c.307C>T (p.Arg103Trp)
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2022 · PMID 35580588 · open access
Questions about rs61734651
What is rs61734651?
rs61734651 is a single position in the genome, in or near the COL9A3 gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs61734651 linked to?
On MyGeneLog this position is linked to Age-Related Hearing Loss. The research behind each link, and its sources, are set out on that condition page.
Does having rs61734651 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs61734651 come from?
GWAS Catalog, American journal of human genetics 2022, PMID:35580588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 16122227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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