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Systolic blood pressure (MTAG)

MYH6 · rs61731179

Where this position leads

Condition: Blood Pressure

rs61731179 Condition: Blood Pressure Blood Pressure Condition rs61731179 rs61731179 MYH6

What the study found

Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the A allele shifted the measure 0.022 higher (95% confidence interval 0.015-0.029); p = 8 × 10−9.

Where it sits Chromosome 14, band 14q11.2 — a synonymous change in MYH6.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Systolic blood pressure (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Systolic blood pressure (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs61731179

What is rs61731179?

rs61731179 is a single position in the genome, in or near the MYH6 gene. Published research associates it with systolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61731179 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs61731179 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61731179 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (MTAG) (rs61731179). MyGeneLog™. https://www.mygenelog.com/variants/rs61731179

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