Sensitive

Myocardial infarction

ARHGAP42 · rs61621482

Where this position leads

Condition: Myocardial Infarction

rs61621482 Condition: Myocardial Infarction Myocardial Infarction Condition rs61621482 rs61621482 ARHGAP42

What the study found

Who was studied 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls.

The effect Each copy of the G allele carried 1.05 times the odds of Myocardial infarction (95% confidence interval 1.03-1.07); p = 8 × 10−9.

How common The G allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 11, band 11q22.1 — in an intron of ARHGAP42.

What each result means

C/C No copy of the version the research linked to Myocardial infarction. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Myocardial infarction. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Myocardial infarction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs61621482

What is rs61621482?

rs61621482 is a single position in the genome, in or near the ARHGAP42 gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61621482 linked to?

On MyGeneLog this position is linked to Myocardial Infarction. The research behind each link, and its sources, are set out on that condition page.

Does having rs61621482 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61621482 come from?

GWAS Catalog, European heart journal 2021, PMID:33532862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Myocardial infarction (rs61621482). MyGeneLog™. https://www.mygenelog.com/variants/rs61621482

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