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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.000784 lower (95% confidence interval 0.00051-0.00106); p = 1 × 10−8.
How common The T allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 6, band 6q21 — in an intron of AFG1L.
What each result means
C/CNo copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs61598054
What is rs61598054?
rs61598054 is a single position in the genome, in or near the AFG1L gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs61598054 linked to?
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Does having rs61598054 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs61598054 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1822113Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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