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APMAP protein level (protein group normalized intensity)

APMAP · rs6138438

What the study found

Who was studied 1,257 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.513 higher (95% confidence interval 0.41-0.62); p = 7 × 10−22.

How common The C allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 20, band 20p11.21 — in an intron of APMAP.

What each result means

C/C Two copies of the version the research linked to APMAP protein level (protein group normalized intensity). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to APMAP protein level (protein group normalized intensity). That is a smaller link than two copies.
G/G No copy of the version the research linked to APMAP protein level (protein group normalized intensity). This is the starting point the study compared everyone against.
Source

Questions about rs6138438

What is rs6138438?

rs6138438 is a single position in the genome, in or near the APMAP gene. Published research associates it with apmap protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6138438 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6138438 come from?

GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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APMAP protein level (protein group normalized intensity) (rs6138438). MyGeneLog™. https://www.mygenelog.com/variants/rs6138438

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