Standard

Triglycerides

LRP1 · rs61352607

Where this position leads

Condition: High Triglycerides

rs61352607 Condition: High Triglycerides High Triglycerides Condition rs61352607 rs61352607 LRP1

What the study found

Who was studied up to 62,166 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.038 s.d. higher (95% confidence interval 0.024-0.052); p = 1 × 10−8.

How common The G allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 12, band 12q13.3 — in an intron of INHBC.

What each result means

G/G Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

Questions about rs61352607

What is rs61352607?

rs61352607 is a single position in the genome, in or near the LRP1 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61352607 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs61352607 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61352607 come from?

GWAS Catalog, Nat Genet 2015, PMID:25961943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs61352607). MyGeneLog™. https://www.mygenelog.com/variants/rs61352607

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