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Leucine-rich repeat transmembrane protein FLRT3 levels

MACROD2 · rs6135229

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.615 lower (95% confidence interval 0.56-0.67); p = 5 × 10−111.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 20, band 20p12.1 — in an intron of MACROD2.

What each result means

A/A Two copies of the version the research linked to Leucine-rich repeat transmembrane protein FLRT3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT3 levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT3 levels. This is the starting point the study compared everyone against.
Source

Questions about rs6135229

What is rs6135229?

rs6135229 is a single position in the genome, in or near the MACROD2 gene. Published research associates it with leucine-rich repeat transmembrane protein flrt3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6135229 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6135229 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Leucine-rich repeat transmembrane protein FLRT3 levels (rs6135229). MyGeneLog™. https://www.mygenelog.com/variants/rs6135229

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