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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 449,734 European ancestry individuals; replicated in 248,098 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−11.
How common The T allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 20, band 20p12.1 — between genes, 16.9 kb from PPIAP17.
What each result means
G/GNo copy of the version the research linked to Chronotype. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Chronotype. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Chronotype. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 30696823 · open access
Questions about rs6131805
What is rs6131805?
rs6131805 is a single position in the genome, in or near the MACROD2 gene. Published research associates it with chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6131805 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6131805 come from?
GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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