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Neonatal circulating Complement Component 4 (C4) protein concentration

LINC00533 · rs61229539

What the study found

Who was studied 68,768 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.11 lower (95% confidence interval 0.09-0.13); p = 2 × 10−80.

Where it sits Chromosome 6, band 6p22.1 — in an intron of LINC00533.

What each result means

C/C Two copies of the version the research linked to Neonatal circulating Complement Component 4 (C4) protein concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Neonatal circulating Complement Component 4 (C4) protein concentration. That is a smaller link than two copies.
T/T No copy of the version the research linked to Neonatal circulating Complement Component 4 (C4) protein concentration. This is the starting point the study compared everyone against.
Source

Questions about rs61229539

What is rs61229539?

rs61229539 is a single position in the genome, in or near the LINC00533 gene. Published research associates it with neonatal circulating complement component 4 (c4) protein concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61229539 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61229539 come from?

GWAS Catalog, Cell genomics 2023, PMID:38116117. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neonatal circulating Complement Component 4 (C4) protein concentration (rs61229539). MyGeneLog™. https://www.mygenelog.com/variants/rs61229539

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