Standard
JT interval
TRPC4AP · rs6120819
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 212,199 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0365 lower (95% confidence interval 0.029-0.044); p = 4 × 10−20.
How common The T allele had a frequency of about 81% in the people studied.
Where it sits Chromosome 20, band 20q11.22 — in an intron of TRPC4AP.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of JT interval — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with JT interval.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of JT interval compared to the general population.
Source
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
Young WJ,
Lahrouchi N,
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Duong T,
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Brody JA,
Salman R,
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Nature communications · 2022 · PMID 36050321 · open access
Questions about rs6120819
What is rs6120819?
rs6120819 is a single position in the genome, in or near the TRPC4AP gene. Published research associates it with jt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6120819 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6120819 come from?
GWAS Catalog, Nature communications 2022, PMID:36050321. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
JT interval (rs6120819). MyGeneLog™. https://www.mygenelog.com/variants/rs6120819
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