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Voltage-dependent calcium channel subunit alpha-2/delta-3 levels

near CACNA2D3 · rs61200186

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.143 lower (95% confidence interval 0.11-0.18); p = 4 × 10−17.

How common The A allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — between genes, 16 kb from CACNA2D3.

What each result means

A/A Two copies of the version the research linked to Voltage-dependent calcium channel subunit alpha-2/delta-3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Voltage-dependent calcium channel subunit alpha-2/delta-3 levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Voltage-dependent calcium channel subunit alpha-2/delta-3 levels. This is the starting point the study compared everyone against.
Source

Questions about rs61200186

What is rs61200186?

rs61200186 is a single position in the genome, in or near the near CACNA2D3 gene. Published research associates it with voltage-dependent calcium channel subunit alpha-2/delta-3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs61200186 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61200186 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Voltage-dependent calcium channel subunit alpha-2/delta-3 levels (rs61200186). MyGeneLog™. https://www.mygenelog.com/variants/rs61200186

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